1839
Some of Anne's physical symptoms are evident in the illustration: discolouration, swelling, and loss of tissue. Walking would have been difficult and painful. She had probably been suffering with the condition for quite some time before seeking medical attention. It is likely that, to survive, Anne would have had to have both feet amputated.
The images were created at different times – note the subtle changes in skin texture and the size of the sores. Medical illustrations were important in recording textures and colours that indicate specific diseases. In this case, gangrene.